OXYGEN AND LDL TRANSPORT IN ARTERIES
OXYGEN TRANSPORT: SHERWOOD NUMBER (Sh)

- High Sh at the apex region
- Outer wall: Low oxygen transfer into the wall during the cycle
- Pericardial wall: Downstream increase of mass transfer
OXYGEN TRANSPORT
Conventional type anastomosis

Wall shear stress (WSS) contours on artery floor

Normalized wall flux (Sherwood number) contours on artery floor

Þ Correlation of low WSS and decreased oxygen flux into the wall.
Clinical observation: Artery floor IH in this region
vein graft anastomosis!
LDL SURFACE CONCENTRATION
Influence of flow separation

Axisym. stenosed tube (75% occl.)
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Wall concentration, dev. over the length | Concentration profiles |
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Concentration contours | Streamlines |
- Concentration increase in the separation zone
- Flow separation influences the conc. boundary layer ? decrease of the surface conc.
ÞLDL concentration at the endothelium is affected by fluid vel. near the wall
MACROMOLECULE TRANSPORT, filtration and diffusion

Locally 10% LDL increase at the outer sinus wall.
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