Computer simulation of vascular flow and mass transport
Research topics
Numerical methods are useful in supporting experimental methods
and often enable the determination of flow variables which are
difficult to obtain in experiments (e.g. wall shear stress).
The scientific activities of the Computational Biofluid Mechanics
group at the University of Technology in Graz include
- Numerical simulation of 3D-flow in complex geometric domains (arterial bifurcations)
- Numerical simulation of non-Newtonian flow (inelastic behavior using appropriate shear
thinning models, visco-elastic flow)
- Fluid-structure interaction problems (Numerical simulation of flowin arteries
with distensible walls (moving boundary problems) are calculated under physiological
time-dependent pressure loading)
- Numerical analyis of transport processes in large arteries (The luminal transport
and the wall mass transfer of various substances like gases and macro-molecules is
analyzed in 2D and 3D computational domains)
- Simulation of the transport process of thrombogenic substances (The convective
diffusion of Thromboxane A2, Prothrombin, Thrombin and Antithrombin and the chemical
reactions between them are simulated in 3D-Finite-Element models)
- Numerical flow studies in various models of bypass anastomoses - optimal design studies
- Numerical grid generation (A grid generator for complex 3D-finite element
grids was developed based on 3D-approximating splines and a local optimization
algorithm. The generator is especially suited for the generation of bifurcation-grids
based on experimentally measured surface data)
Selected studies
FLOW DYNAMICS
MASS TRANSPORT
Involved: Karl Perktold, Martin Prosi, Armin Leuprecht, Gerhard Karner, Tanja Brandl.